Stroke occurs when a vessel that supplies blood to the brain ruptures or becomes blocked, starving brain cells of oxygen and resulting in brain damage. It is the fourth leading cause of death in the U.S., as well as a leading cause of serious, long-term disability in adults, affecting about 795,000 Americans and killing 137,000 people – one every four minutes – every year. Given those stark statistics and the fact that stroke is preventable, knowing your personal risk factors for stroke is essential.