Sepsis is a serious and often life-threatening complication of an infection. It occurs when the body has an overwhelming response to a bacterial infection, releasing infection-fighting chemicals into the bloodstream that trigger inflammation throughout the body. This inflammation can lead to blood clots and leaky blood vessels, which causes poor blood flow, depriving the body and its organs of the oxygen and nutrients needed to function effectively. In severe cases, organs may fail. In the worst cases, a dangerous drop in blood pressure occurs and the heart is weakened, leading to a life-threatening condition called septic shock.